# Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

> **NCT02582008** · EARLY_PHASE1 · TERMINATED · sponsor: **Wake Forest University Health Sciences** · enrollment: 9 (actual)

## Conditions studied

- Current Smoker
- Head and Neck Squamous Cell Carcinoma
- Hypopharyngeal Squamous Cell Carcinoma
- Laryngeal Squamous Cell Carcinoma
- Nasopharyngeal Carcinoma
- Oral Cavity Squamous Cell Carcinoma
- Oropharyngeal Squamous Cell Carcinoma

## Interventions

- **DRUG:** Bupropion Hydrochloride
- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Nicotine Replacement
- **OTHER:** Quality-of-Life Assessment
- **OTHER:** Questionnaire Administration
- **DRUG:** Varenicline

## Key facts

- **NCT ID:** NCT02582008
- **Lead sponsor:** Wake Forest University Health Sciences
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2016-01
- **Primary completion:** 2018-10-06
- **Final completion:** 2019-09-06
- **Target enrollment:** 9 (ACTUAL)
- **Why stopped:** Slow accrual
- **Last updated:** 2023-03-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02582008

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02582008, "Bupropion Hydrochloride or Patient's Choice for Smoking Cessation in Patients With Squamous Cell Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy". Retrieved via AI Analytics 2026-06-11 from https://api.ai-analytics.org/clinical/NCT02582008. Licensed CC0.

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