# Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft

> **NCT02592330** · PHASE1,PHASE2 · COMPLETED · sponsor: **Massachusetts Eye and Ear Infirmary** · enrollment: 23 (actual)

## Conditions studied

- Limbal Stem Cell Deficiency

## Interventions

- **PROCEDURE:** Biopsy to collect limbal epithelial stem cells that will be cultivated into a graft
- **BIOLOGICAL:** Cultivation of Limbal epithelial cells into a graft
- **PROCEDURE:** CALEC Transplant

## Key facts

- **NCT ID:** NCT02592330
- **Lead sponsor:** Massachusetts Eye and Ear Infirmary
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-08-01
- **Primary completion:** 2023-03-31
- **Final completion:** 2023-03-31
- **Target enrollment:** 23 (ACTUAL)
- **Last updated:** 2025-01-15

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02592330

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02592330, "Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT02592330. Licensed CC0.

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