# Metformin for the Prevention of Episodic Migraine (MPEM)

> **NCT02593097** · PHASE3 · COMPLETED · sponsor: **Mayo Clinic** · enrollment: 34 (actual)

## Conditions studied

- Migraine

## Interventions

- **DRUG:** Metformin
- **DRUG:** Matching Placebo

## Key facts

- **NCT ID:** NCT02593097
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-02
- **Primary completion:** 2019-06
- **Final completion:** 2019-06
- **Target enrollment:** 34 (ACTUAL)
- **Last updated:** 2020-07-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02593097

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02593097, "Metformin for the Prevention of Episodic Migraine (MPEM)". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT02593097. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
