# Depot-opioids for Pre- and Postoperative Pain Relief After Primary Knee Arthroplasty.Tapentadol vs Oxycodone vs Placebo

> **NCT02604446** · PHASE3 · COMPLETED · sponsor: **St. Olavs Hospital** · enrollment: 134 (actual)

## Conditions studied

- Joint Diseases

## Interventions

- **DRUG:** Tapentadol
- **DRUG:** Oxycodone
- **DRUG:** Placebo
- **DRUG:** usual pain treatment

## Key facts

- **NCT ID:** NCT02604446
- **Lead sponsor:** St. Olavs Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-09
- **Primary completion:** 2019-02
- **Final completion:** 2019-02
- **Target enrollment:** 134 (ACTUAL)
- **Last updated:** 2021-11-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02604446

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02604446, "Depot-opioids for Pre- and Postoperative Pain Relief After Primary Knee Arthroplasty.Tapentadol vs Oxycodone vs Placebo". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT02604446. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
