# TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence

> **NCT02621645** · PHASE4 · RECRUITING · sponsor: **Universitaire Ziekenhuizen KU Leuven** · enrollment: 126 (estimated)

## Conditions studied

- Twin Reversal Arterial Perfusion Syndrome

## Interventions

- **PROCEDURE:** Early selective reduction of TRAP mass
- **PROCEDURE:** Late selective reduction of TRAP mass
- **DEVICE:** Ultrasound-guided intrafetal ablation using a 18 to 20 Gauge needle
- **DEVICE:** Ultrasound-guided intrafetal ablation using a 17 to 20 Gauge needle
- **DEVICE:** Laser coagulation of the cord or anastomising vessels through a 17 Gauge to 7 French trocar, with a 1-1,3 mm fetoscope and a 400 µm laser fiber

## Key facts

- **NCT ID:** NCT02621645
- **Lead sponsor:** Universitaire Ziekenhuizen KU Leuven
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2016-05
- **Primary completion:** 2025-06
- **Final completion:** 2025-06
- **Target enrollment:** 126 (ESTIMATED)
- **Last updated:** 2024-07-10

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02621645

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02621645, "TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT02621645. Licensed CC0.

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