# Ultrasound to Enhance Paclitaxel Uptake in Critical Limb Ischemia: the PACUS Trial

> **NCT02625740** · NA · COMPLETED · sponsor: **University of Rome Tor Vergata** · enrollment: 56 (actual)

## Conditions studied

- Peripheral Arterial Disease, Angioplasty

## Interventions

- **DEVICE:** Local exposition of target lesion to high intensity, low-frequency ultrasound
- **DEVICE:** drug eluting ballon angioplasty
- **DEVICE:** Flow occlusion with an angioplasty balloon
- **DRUG:** Local Paclitaxel infusion
- **PROCEDURE:** Angiographic control

## Key facts

- **NCT ID:** NCT02625740
- **Lead sponsor:** University of Rome Tor Vergata
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-11
- **Primary completion:** 2014-11
- **Final completion:** 2015-11
- **Target enrollment:** 56 (ACTUAL)
- **Last updated:** 2015-12-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02625740

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02625740, "Ultrasound to Enhance Paclitaxel Uptake in Critical Limb Ischemia: the PACUS Trial". Retrieved via AI Analytics 2026-06-14 from https://api.ai-analytics.org/clinical/NCT02625740. Licensed CC0.

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