Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation
ACTIVE_NOT_RECRUITING
Status
Conditions
- Newly Diagnosed Acute Myeloid Leukemia (AML)
- Untreated AML
- AML Arising From Myelodysplastic Syndrome (MDS)
- AML Arising From Antecedent Hematologic Disorder (AHD)
- AML Arising After Exposure to Genotoxic Injury
Interventions
- DRUG: AG-120
- DRUG: AG-221
- DRUG: cytarabine
- DRUG: daunorubicin
- DRUG: idarubicin
- DRUG: mitoxantrone
- DRUG: etoposide
Sponsor
Institut de Recherches Internationales Servier
Collaborators