# HP Xenon-129 fMRI of Healthy Volunteers and Participants With Alzheimer's Disease

> **NCT02638519** · EARLY_PHASE1 · TERMINATED · sponsor: **Thunder Bay Regional Health Research Institute** · enrollment: 51 (actual)

## Conditions studied

- Alzheimer Disease

## Interventions

- **OTHER:** Traditional Proton fMRI
- **OTHER:** Hyperpolarized Xenon-129 fMRI
- **DRUG:** Hyperpolarized Xenon-129
- **DEVICE:** 1H-129Xe Dual-Tuned Quadrature Head Coil

## Key facts

- **NCT ID:** NCT02638519
- **Lead sponsor:** Thunder Bay Regional Health Research Institute
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2016-06-27
- **Primary completion:** 2022-04-19
- **Final completion:** 2022-04-19
- **Target enrollment:** 51 (ACTUAL)
- **Why stopped:** Unable to reach the target enrollment of 40 participants with Alzheimer's disease.
- **Last updated:** 2024-10-15

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02638519

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02638519, "HP Xenon-129 fMRI of Healthy Volunteers and Participants With Alzheimer's Disease". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT02638519. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
