# Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations

> **NCT02646319** · EARLY_PHASE1 · COMPLETED · sponsor: **Mayo Clinic** · enrollment: 2 (actual)

## Conditions studied

- Advanced Malignant Neoplasm
- Cervical Squamous Cell Carcinoma
- Endometrial Carcinoma
- Malignant Uterine Neoplasm
- Recurrent Bladder Carcinoma
- Recurrent Breast Carcinoma
- Recurrent Cervical Carcinoma
- Recurrent Head and Neck Carcinoma
- Recurrent Malignant Neoplasm
- Recurrent Ovarian Carcinoma
- Recurrent Prostate Carcinoma
- Recurrent Renal Cell Carcinoma
- Solid Neoplasm
- Stage III Bladder Cancer
- Stage III Prostate Cancer
- Stage III Renal Cell Cancer
- Stage IIIA Breast Cancer
- Stage IIIA Cervical Cancer
- Stage IIIA Ovarian Cancer
- Stage IIIB Breast Cancer
- Stage IIIB Cervical Cancer
- Stage IIIB Ovarian Cancer
- Stage IIIC Breast Cancer
- Stage IIIC Ovarian Cancer
- Stage IV Breast Cancer
- Stage IV Ovarian Cancer
- Stage IV Prostate Cancer
- Stage IV Renal Cell Cancer
- Stage IVA Bladder Cancer
- Stage IVA Cervical Cancer
- Stage IVB Bladder Cancer
- Stage IVB Cervical Cancer

## Interventions

- **OTHER:** Laboratory Biomarker Analysis
- **DRUG:** Nanoparticle Albumin-Bound Rapamycin
- **OTHER:** Quality-of-Life Assessment

## Key facts

- **NCT ID:** NCT02646319
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-01
- **Primary completion:** 2017-09-05
- **Final completion:** 2018-04-24
- **Target enrollment:** 2 (ACTUAL)
- **Last updated:** 2019-06-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02646319

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02646319, "Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT02646319. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*