WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome
Conditions
- Chronic Myelomonocytic Leukemia
- Myelodysplastic Syndrome With Isolated Del(5q)
- Myelodysplastic/Myeloproliferative Neoplasm
- Previously Treated Myelodysplastic Syndrome
- Recurrent Adult Acute Myeloid Leukemia
- Untreated Adult Acute Myeloid Leukemia
Interventions
- DRUG: Cytarabine
- OTHER: Laboratory Biomarker Analysis
- OTHER: Pharmacological Study
- OTHER: Quality-of-Life Assessment
- OTHER: Questionnaire Administration
- DRUG: WEE1 Inhibitor AZD1775
Sponsor
Mayo Clinic
Collaborators