# A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy

> **NCT02693119** · PHASE2 · COMPLETED · sponsor: **Stealth BioTherapeutics Inc.** · enrollment: 12 (actual)

## Conditions studied

- Leber's Hereditary Optic Neuropathy

## Interventions

- **DRUG:** elamipretide (MTP-131) 1% topical ophthalmic solution
- **DRUG:** Vehicle topical ophthalmic solution

## Key facts

- **NCT ID:** NCT02693119
- **Lead sponsor:** Stealth BioTherapeutics Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-03
- **Primary completion:** 2019-09
- **Final completion:** 2019-12
- **Target enrollment:** 12 (ACTUAL)
- **Last updated:** 2021-11-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02693119

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02693119, "A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT02693119. Licensed CC0.

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