# Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy With Ex Vivo Generated Polyomavirus-Specific T-Cells

> **NCT02694783** · EARLY_PHASE1 · COMPLETED · sponsor: **National Institute of Neurological Disorders and Stroke (NINDS)** · enrollment: 60 (actual)

## Conditions studied

- Progressive Multifocal Leukoencephalopathy

## Interventions

- **BIOLOGICAL:** PyVST

## Key facts

- **NCT ID:** NCT02694783
- **Lead sponsor:** National Institute of Neurological Disorders and Stroke (NINDS)
- **Sponsor class:** NIH
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-03-28
- **Primary completion:** 2019-12-13
- **Final completion:** 2020-03-06
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2026-05-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02694783

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02694783, "Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy With Ex Vivo Generated Polyomavirus-Specific T-Cells". Retrieved via AI Analytics 2026-07-04 from https://api.ai-analytics.org/clinical/NCT02694783. Licensed CC0.

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