# Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life

> **NCT02701088** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Centre Francois Baclesse** · enrollment: 71 (actual)

## Conditions studied

- Locally Advanced Anal Canal Cancer

## Interventions

- **DRUG:** 5Fluorouracile and Mitomycin-C
- **RADIATION:** Simultaneously integrated boost of intensity modulated radiation therapy (SIB-IMRT) by tomotherapy

## Key facts

- **NCT ID:** NCT02701088
- **Lead sponsor:** Centre Francois Baclesse
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2015-12
- **Primary completion:** 2021-06-25
- **Final completion:** 2025-12
- **Target enrollment:** 71 (ACTUAL)
- **Last updated:** 2025-09-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02701088

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02701088, "Study of SIB-IMRT in Combination With 5-FU and Mitomycin-C Among Patients With Locally Advanced Anal Canal Cancer: Efficacy, Safety and Quality of Life". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT02701088. Licensed CC0.

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