# The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit

> **NCT02705378** · PHASE3 · WITHDRAWN · sponsor: **Massachusetts General Hospital**

## Conditions studied

- Constipation
- Critical Illness

## Interventions

- **DRUG:** Polyethylene glycol
- **DRUG:** naloxegol

## Key facts

- **NCT ID:** NCT02705378
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2017-05
- **Primary completion:** 2019-04
- **Final completion:** 2019-12
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** PI left institution. Protocol never submitted to the IRB, no contract executed only Confidentiality Agreement, and study not done.
- **Last updated:** 2021-05-05

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02705378

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02705378, "The Effect of Naloxegol on Refractory Constipation in the Intensive Care Unit". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT02705378. Licensed CC0.

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