High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure

Conditions

• Acute Liver Failure

Interventions

• BIOLOGICAL: Plasma Exchange
• OTHER: Management of cerebral edema/intracranial hypertension:
• OTHER: Transfer to Intensive Care Unit
• DRUG: Prophylactic Antibiotics
• OTHER: Intubation of trachea
• OTHER: Administration of mannitol or 3% saline for severe elevation of Intra Cranial Pressure
• OTHER: Volume Replacement
• OTHER: Pressor Support
• DRUG: N-acetyl-L-cysteine
• OTHER: Correction of metabolic parameters
• DIETARY_SUPPLEMENT: Correction of nutrition

Sponsor

Institute of Liver and Biliary Sciences, India