# Autoimmune Basis for Postural Tachycardia Syndrome

> **NCT02725060** · NA · ENROLLING_BY_INVITATION · sponsor: **Vanderbilt University Medical Center** · enrollment: 58 (estimated)

## Conditions studied

- Postural Orthostatic Tachycardia Syndrome
- Postural Tachycardia Syndrome
- Tachycardia
- Arrhythmias, Cardiac
- Autonomic Nervous System Diseases
- Orthostatic Intolerance
- Cardiovascular Diseases
- Primary Dysautonomias

## Interventions

- **DRUG:** phenylephrine
- **DRUG:** isoproterenol
- **RADIATION:** 25 micro-Ci of radiation
- **PROCEDURE:** Posture study with blood samples
- **PROCEDURE:** 24-hour heart rhythm and blood pressure monitoring
- **PROCEDURE:** Quantitative Axonal Sudomotor Reflex Testing
- **PROCEDURE:** Autonomic function tests
- **OTHER:** Rebreathing test
- **OTHER:** Assessment of splanchnic capacitance
- **PROCEDURE:** microneurography

## Key facts

- **NCT ID:** NCT02725060
- **Lead sponsor:** Vanderbilt University Medical Center
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2016-02
- **Primary completion:** 2026-10
- **Final completion:** 2026-12
- **Target enrollment:** 58 (ESTIMATED)
- **Last updated:** 2025-11-12

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02725060

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02725060, "Autoimmune Basis for Postural Tachycardia Syndrome". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT02725060. Licensed CC0.

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