# PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome

> **NCT02743377** · PHASE1,PHASE2 · COMPLETED · sponsor: **National Institute of Mental Health (NIMH)** · enrollment: 16 (actual)

## Conditions studied

- Nervous System Disease

## Interventions

- **OTHER:** Brain PET Imaging with 11C Rolipram
- **DRUG:** Whole Body PET Baseline with 11C Rolipram
- **DRUG:** Whole Body PET Blocked with Roflumilast

## Key facts

- **NCT ID:** NCT02743377
- **Lead sponsor:** National Institute of Mental Health (NIMH)
- **Sponsor class:** NIH
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2018-04-04
- **Primary completion:** 2019-10-23
- **Final completion:** 2020-05-19
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2020-10-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02743377

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02743377, "PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT02743377. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*