# Comparison of Vonoprazan to Esomeprazole in Participants With Symptomatic GERD Who Responded Partially to a High Dose of Proton Pump Inhibitor (PPI)

> **NCT02743949** · PHASE2 · COMPLETED · sponsor: **Takeda** · enrollment: 256 (actual)

## Conditions studied

- Gastroesophageal Reflux

## Interventions

- **DRUG:** Vonoprazan
- **DRUG:** Esomeprazole
- **DRUG:** Esomeprazole Placebo

## Key facts

- **NCT ID:** NCT02743949
- **Lead sponsor:** Takeda
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-07-14
- **Primary completion:** 2018-10-05
- **Final completion:** 2018-10-12
- **Target enrollment:** 256 (ACTUAL)
- **Last updated:** 2020-02-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02743949

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02743949, "Comparison of Vonoprazan to Esomeprazole in Participants With Symptomatic GERD Who Responded Partially to a High Dose of Proton Pump Inhibitor (PPI)". Retrieved via AI Analytics 2026-07-10 from https://api.ai-analytics.org/clinical/NCT02743949. Licensed CC0.

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