# Myocardial Protection With Phosphocreatine in High-RIsk Cardiac SurgEry Patients

> **NCT02757443** · PHASE3 · COMPLETED · sponsor: **Meshalkin Research Institute of Pathology of Circulation** · enrollment: 120 (actual)

## Conditions studied

- Cardiac Surgical Procedures
- Heart Valve Prosthesis Implantation

## Interventions

- **DRUG:** Phosphocreatine sodium tetrahydrate after anaesthesia induction
- **DRUG:** 5% Glucose after anaesthesia induction
- **DRUG:** Phosphocreatine sodium tetrahydrate added to cardioplegia
- **DRUG:** 5% Glucose
- **DRUG:** Phosphocreatine sodium tetrahydrate after heart recovery
- **DRUG:** 5% Glucose after heart recovery
- **DRUG:** Phosphocreatine sodium tetrahydrate after ICU admission
- **DRUG:** 5% Glucose after ICU admission

## Key facts

- **NCT ID:** NCT02757443
- **Lead sponsor:** Meshalkin Research Institute of Pathology of Circulation
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-06
- **Primary completion:** 2021-04
- **Final completion:** 2021-05
- **Target enrollment:** 120 (ACTUAL)
- **Last updated:** 2021-07-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02757443

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02757443, "Myocardial Protection With Phosphocreatine in High-RIsk Cardiac SurgEry Patients". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02757443. Licensed CC0.

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