# Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastases

> **NCT02758951** · PHASE2,PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **Koen Rovers** · enrollment: 358 (actual)

## Conditions studied

- Colorectal Neoplasm
- Colorectal Cancer
- Colorectal Neoplasms Malignant
- Colorectal Carcinoma
- Colorectal Adenocarcinoma
- Peritoneal Neoplasms
- Peritoneal Carcinomatosis
- Peritoneal Cancer
- Peritoneal Metastases
- Peritoneal Neoplasm Malignant Secondary Carcinomatosis
- Peritoneal Neoplasm Malignant Secondary

## Interventions

- **OTHER:** Perioperative systemic therapy
- **COMBINATION_PRODUCT:** Perioperative CAPOX-bevacizumab
- **COMBINATION_PRODUCT:** Perioperative FOLFOX-bevacizumab
- **COMBINATION_PRODUCT:** Perioperative FOLFIRI-bevacizumab
- **PROCEDURE:** CRS-HIPEC, experimental arm
- **PROCEDURE:** CRS-HIPEC, control arm

## Key facts

- **NCT ID:** NCT02758951
- **Lead sponsor:** Koen Rovers
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2017-06-01
- **Primary completion:** 2024-10-31
- **Final completion:** 2029-06-01
- **Target enrollment:** 358 (ACTUAL)
- **Last updated:** 2026-03-24

## Collaborators

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- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02758951

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02758951, "Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastases". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT02758951. Licensed CC0.

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