# Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

> **NCT02760849** · NA · ACTIVE_NOT_RECRUITING · sponsor: **M.D. Anderson Cancer Center** · enrollment: 374 (actual)

## Conditions studied

- Deleterious BARD1 Gene Mutation
- Deleterious BRCA1 Gene Mutation
- Deleterious BRCA2 Gene Mutation
- Deleterious BRIP1 Gene Mutation
- Deleterious EPCAM Gene Mutation
- Deleterious MLH1 Gene Mutation
- Deleterious MSH2 Gene Mutation
- Deleterious MSH6 Gene Mutation
- Deleterious PALB2 Gene Mutation
- Deleterious PMS2 Gene Mutation
- Deleterious RAD51C Gene Mutation
- Deleterious RAD51D Gene Mutation
- Hereditary Breast and Ovarian Cancer Syndrome
- Premenopausal

## Interventions

- **OTHER:** Laboratory Biomarker Analysis
- **PROCEDURE:** Oophorectomy
- **OTHER:** Quality-of-Life Assessment
- **PROCEDURE:** Salpingectomy
- **PROCEDURE:** Salpingo-Oophorectomy

## Key facts

- **NCT ID:** NCT02760849
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2016-05-02
- **Primary completion:** 2041-05-31
- **Final completion:** 2041-05-31
- **Target enrollment:** 374 (ACTUAL)
- **Last updated:** 2026-01-07

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02760849

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02760849, "Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02760849. Licensed CC0.

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