# The Efficacy of Denosumab in Decreasing Periprosthetic Bone Loss in Patients With Total Knee Arthroplasty

> **NCT02760979** · PHASE4 · COMPLETED · sponsor: **Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau** · enrollment: 60 (actual)

## Conditions studied

- Bone Resorption

## Interventions

- **DRUG:** Denosumab
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02760979
- **Lead sponsor:** Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-01
- **Primary completion:** 2014-01
- **Final completion:** 2015-06
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2017-08-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02760979

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02760979, "The Efficacy of Denosumab in Decreasing Periprosthetic Bone Loss in Patients With Total Knee Arthroplasty". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT02760979. Licensed CC0.

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