Gene-Modified T Cells, Vaccine Therapy, and Nivolumab in Treating Patients With Stage IV or Locally Advanced Solid Tumors Expressing NY-ESO-1

Conditions

• Adult Solid Neoplasm
• Childhood Solid Neoplasm
• Metastatic Neoplasm

Interventions

• BIOLOGICAL: Aldesleukin
• DRUG: Cyclophosphamide
• DRUG: Fludarabine Phosphate
• OTHER: Laboratory Biomarker Analysis
• BIOLOGICAL: Nivolumab
• BIOLOGICAL: NY-ESO-1 Reactive TCR Retroviral Vector Transduced Autologous PBL
• BIOLOGICAL: NY-ESO-1(157-165) Peptide-pulsed Autologous Dendritic Cell Vaccine
• PROCEDURE: Positron Emission Tomography

Sponsor

Jonsson Comprehensive Cancer Center

Collaborators

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