Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency
Conditions
- Breast Cancer
- Triple Negative Breast Neoplasms
- HRpos Breast Neoplasms
- BRCA 1 /2 and / or HRD
Interventions
- DRUG: PwO
- DRUG: PwCb
- DRUG: EC
- PROCEDURE: Surgery after neoadjuvant Therapy
- OTHER: Stratification
Sponsor
GBG Forschungs GmbH
Collaborators