Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia

NCT02791919 · clinicaltrials.gov ↗

PHASE1

Phase

WITHDRAWN

Status

NIH

Sponsor class

Stopped Other - Protocol moved to Disapproved

Conditions

CNS 2a
CNS 2b
CNS 2c
CNS1
Recurrent Adult Acute Myeloid Leukemia
Recurrent Childhood Acute Myeloid Leukemia

Interventions

DRUG: Cytarabine
BIOLOGICAL: Filgrastim
DRUG: Fludarabine Phosphate
OTHER: Laboratory Biomarker Analysis
OTHER: Pharmacological Study
DRUG: WEE1 Inhibitor AZD1775

Sponsor

National Cancer Institute (NCI)