# Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery

> **NCT02807428** · PHASE2 · COMPLETED · sponsor: **Adynxx, Inc.** · enrollment: 210 (actual)

## Conditions studied

- Post-surgical Pain

## Interventions

- **DRUG:** AYX1 Injection 660 mg/6 mL
- **DRUG:** Placebo Injection 6 mL

## Key facts

- **NCT ID:** NCT02807428
- **Lead sponsor:** Adynxx, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-02-20
- **Primary completion:** 2017-10-23
- **Final completion:** 2017-12-19
- **Target enrollment:** 210 (ACTUAL)
- **Last updated:** 2018-10-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02807428

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02807428, "Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT02807428. Licensed CC0.

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