# CADASIL Disease Discovery

> **NCT02821780** · — · COMPLETED · sponsor: **National Heart, Lung, and Blood Institute (NHLBI)** · enrollment: 20 (actual)

## Conditions studied

- Germline Mutation in the NOTCH 3 Gene
- Cardiovascular Disease
- Arterial Stiffness
- Pathogenesis of CADASIL
- Clinical Phenotype of CADASIL

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT02821780
- **Lead sponsor:** National Heart, Lung, and Blood Institute (NHLBI)
- **Sponsor class:** NIH
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2016-10-18
- **Primary completion:** 2022-05-03
- **Final completion:** 2022-05-03
- **Target enrollment:** 20 (ACTUAL)
- **Last updated:** 2026-04-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02821780

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02821780, "CADASIL Disease Discovery". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT02821780. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*