# Trial of Radiation and Gene Therapy Before Nivolumab for Metastatic Non-Small Cell Lung Carcinoma and Uveal Melanoma

> **NCT02831933** · PHASE2 · TERMINATED · sponsor: **Eric Bernicker, MD** · enrollment: 11 (actual)

## Conditions studied

- Lung Squamous Cell Carcinoma Stage IV
- Nonsquamous Nonsmall Cell Neoplasm of Lung
- Metastatic Uveal Melanoma

## Interventions

- **BIOLOGICAL:** ADV/HSV-tk
- **DRUG:** Valacyclovir
- **RADIATION:** SBRT
- **DRUG:** nivolumab

## Key facts

- **NCT ID:** NCT02831933
- **Lead sponsor:** Eric Bernicker, MD
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2017-02-15
- **Primary completion:** 2020-11-05
- **Final completion:** 2020-11-05
- **Target enrollment:** 11 (ACTUAL)
- **Why stopped:** Lack of funding
- **Last updated:** 2023-09-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02831933

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02831933, "Trial of Radiation and Gene Therapy Before Nivolumab for Metastatic Non-Small Cell Lung Carcinoma and Uveal Melanoma". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02831933. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*