# Tolerability, Pharmacokinetics and Pharmacodynamics of Six Multiple Rising Dose Regimens of BIA 5-453

> **NCT02840565** · PHASE1 · COMPLETED · sponsor: **Bial - Portela C S.A.** · enrollment: 57 (actual)

## Conditions studied

- Hypertension
- Chronic Heart Failure

## Interventions

- **DRUG:** BIA 5-453
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02840565
- **Lead sponsor:** Bial - Portela C S.A.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2007-09
- **Primary completion:** 2008-07
- **Final completion:** 2008-07
- **Target enrollment:** 57 (ACTUAL)
- **Last updated:** 2016-07-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02840565

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02840565, "Tolerability, Pharmacokinetics and Pharmacodynamics of Six Multiple Rising Dose Regimens of BIA 5-453". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT02840565. Licensed CC0.

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