# Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients

> **NCT02851407** · PHASE3 · COMPLETED · sponsor: **Jazz Pharmaceuticals** · enrollment: 372 (actual)

## Conditions studied

- Veno-occlusive Disease

## Interventions

- **DRUG:** Defibrotide
- **OTHER:** Best Supportive Care

## Key facts

- **NCT ID:** NCT02851407
- **Lead sponsor:** Jazz Pharmaceuticals
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-09-01
- **Primary completion:** 2020-10-20
- **Final completion:** 2020-10-20
- **Target enrollment:** 372 (ACTUAL)
- **Last updated:** 2022-03-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02851407

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02851407, "Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02851407. Licensed CC0.

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