# Sodium-glucose Co-transporter 2 (SGLT2) Inhibitor Risk of Below-Knee Lower Extremity Amputation: A Retrospective Cohort Study Using a Large Claims Database in the United States

> **NCT02857764** · — · COMPLETED · sponsor: **Janssen Research & Development, LLC** · enrollment: 127690 (actual)

## Conditions studied

- Diabetes Mellitus, Type 2

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT02857764
- **Lead sponsor:** Janssen Research & Development, LLC
- **Sponsor class:** INDUSTRY
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2016-02-15
- **Primary completion:** 2017-06-30
- **Final completion:** 2017-06-30
- **Target enrollment:** 127690 (ACTUAL)
- **Last updated:** 2017-08-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02857764

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02857764, "Sodium-glucose Co-transporter 2 (SGLT2) Inhibitor Risk of Below-Knee Lower Extremity Amputation: A Retrospective Cohort Study Using a Large Claims Database in the United States". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT02857764. Licensed CC0.

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