# Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31

> **NCT02859428** · — · TERMINATED · sponsor: **National Institute of Neurological Disorders and Stroke (NINDS)** · enrollment: 51 (actual)

## Conditions studied

- Hereditary Spastic Paraplegia

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT02859428
- **Lead sponsor:** National Institute of Neurological Disorders and Stroke (NINDS)
- **Sponsor class:** NIH
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** TERMINATED
- **Start date:** 2016-11-18
- **Primary completion:** 2020-10-16
- **Final completion:** 2020-10-16
- **Target enrollment:** 51 (ACTUAL)
- **Why stopped:** Investigator left NIH
- **Last updated:** 2020-10-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02859428

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02859428, "Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT02859428. Licensed CC0.

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