Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease

NCT02867800 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

24

Enrollment

OTHER

Sponsor class

Conditions

Sickle Cell Disease
Graft Versus Host Disease

Interventions

DRUG: Diphenhydramine
DRUG: Acetaminophen
DRUG: Methylprednisolone
DRUG: Meperidine
DRUG: Alemtuzumab
DRUG: Thymoglobulin
DRUG: Fludarabine
DRUG: Melphalan
DRUG: Thiotepa
DRUG: Cyclosporine
DRUG: Tacrolimus
DRUG: Methotrexate
DRUG: Abatacept
PROCEDURE: Marrow infusion
DRUG: Sirolimus
DRUG: Mycophenolate Mofetil

Sponsor

Monica Bhatia