# Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

> **NCT02897063** · PHASE1 · RECRUITING · sponsor: **Vanderbilt University Medical Center** · enrollment: 34 (estimated)

## Conditions studied

- Autonomic Failure
- Pure Autonomic Failure
- Multiple System Atrophy
- Parkinson Disease
- Orthostatic Hypotension

## Interventions

- **DRUG:** Droxidopa
- **DRUG:** Midodrine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02897063
- **Lead sponsor:** Vanderbilt University Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2016-09
- **Primary completion:** 2026-09
- **Final completion:** 2026-12
- **Target enrollment:** 34 (ESTIMATED)
- **Last updated:** 2025-10-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02897063

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02897063, "Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT02897063. Licensed CC0.

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