# Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors

> **NCT02905110** · EARLY_PHASE1 · COMPLETED · sponsor: **The University of Texas Health Science Center, Houston** · enrollment: 3 (actual)

## Conditions studied

- Brain Tumor Recurrent

## Interventions

- **DRUG:** Methotrexate
- **DRUG:** Etoposide
- **PROCEDURE:** Ommaya Reservoir

## Key facts

- **NCT ID:** NCT02905110
- **Lead sponsor:** The University of Texas Health Science Center, Houston
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-10-12
- **Primary completion:** 2022-03-04
- **Final completion:** 2022-03-04
- **Target enrollment:** 3 (ACTUAL)
- **Last updated:** 2025-03-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02905110

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02905110, "Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT02905110. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*