Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer

NCT02907918 · clinicaltrials.gov ↗

PHASE2

Phase

TERMINATED

Status

26

Enrollment

OTHER

Sponsor class

Stopped Futility

Conditions

Breast Cancer
Cancer of Breast
Breast Carcinoma

Interventions

DRUG: Palbociclib
DRUG: Letrozole
BIOLOGICAL: Trastuzumab
DRUG: Goserelin
PROCEDURE: Breast surgery
PROCEDURE: Research tumor biopsy
PROCEDURE: Research bone marrow (OPTIONAL)
PROCEDURE: Research blood sample
GENETIC: Research blood for germline DNA
PROCEDURE: Blood for detection of circulating tumor cells

Sponsor

Washington University School of Medicine

Collaborators

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