# Risk Reduction for Alzheimer's Disease

> **NCT02913664** · PHASE2,PHASE3 · COMPLETED · sponsor: **University of Texas Southwestern Medical Center** · enrollment: 513 (actual)

## Conditions studied

- Cognitively Normal Older Adults
- Hypertension
- Subjective Cognitive Decline
- Family History of Alzheimer's Disease

## Interventions

- **DRUG:** Angiotensin II receptor blocker (ARB, losartan) and calcium channel blocker (CCB, amlodipine)
- **BEHAVIORAL:** Aerobic Exercise Training
- **OTHER:** Usual Care
- **BEHAVIORAL:** Stretching Exercise

## Key facts

- **NCT ID:** NCT02913664
- **Lead sponsor:** University of Texas Southwestern Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-02-02
- **Primary completion:** 2021-11-30
- **Final completion:** 2022-01-31
- **Target enrollment:** 513 (ACTUAL)
- **Last updated:** 2022-02-15

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02913664

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02913664, "Risk Reduction for Alzheimer's Disease". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT02913664. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*