# Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

> **NCT02915198** · PHASE4 · RECRUITING · sponsor: **VA Office of Research and Development** · enrollment: 7410 (estimated)

## Conditions studied

- Prediabetic State
- Atherosclerosis
- Metformin

## Interventions

- **DRUG:** Metformin XR
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02915198
- **Lead sponsor:** VA Office of Research and Development
- **Sponsor class:** FED
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-04-03
- **Primary completion:** 2029-09-28
- **Final completion:** 2029-09-28
- **Target enrollment:** 7410 (ESTIMATED)
- **Last updated:** 2025-12-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02915198

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02915198, "Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT02915198. Licensed CC0.

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