Ruxolitinib Phosphate and Chemotherapy Given Before and After Reduced Intensity Donor Stem Cell Transplant in Treating Patients With Myelofibrosis

NCT02917096 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

18

Enrollment

OTHER

Sponsor class

Conditions

Primary Myelofibrosis
Secondary Myelofibrosis

Interventions

PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
DRUG: Fludarabine
DRUG: Fludarabine Phosphate
OTHER: Laboratory Biomarker Analysis
DRUG: Melphalan
OTHER: Pharmacological Study
DRUG: Ruxolitinib
DRUG: Ruxolitinib Phosphate
DRUG: Sirolimus
DRUG: Tacrolimus

Sponsor

City of Hope Medical Center

Collaborators

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