Veliparib, Pembrolizumab, and Combination Chemotherapy in Treating Patient With Locally Advanced Rectal Cancer

NCT02921256 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

363

Enrollment

NIH

Sponsor class

Conditions

Rectal Adenocarcinoma
Stage II Rectal Cancer AJCC v7
Stage III Rectal Cancer AJCC v7

Interventions

DRUG: Capecitabine
DRUG: Fluorouracil
RADIATION: Intensity-Modulated Radiation Therapy
DRUG: Leucovorin
DRUG: Oxaliplatin
BIOLOGICAL: Pembrolizumab
DRUG: Veliparib

Sponsor

National Cancer Institute (NCI)

Collaborators

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