# Leukocyte-rich PRP vs Leukocyte-poor PRP for the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial

> **NCT02923700** · PHASE4 · COMPLETED · sponsor: **Istituto Ortopedico Rizzoli** · enrollment: 192 (actual)

## Conditions studied

- Osteoarthritis

## Interventions

- **BIOLOGICAL:** Leukocyte-rich PRP intra-articular injections
- **BIOLOGICAL:** Leukocyte-poor PRP intra-articular injections

## Key facts

- **NCT ID:** NCT02923700
- **Lead sponsor:** Istituto Ortopedico Rizzoli
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-09-26
- **Primary completion:** 2017-09-26
- **Final completion:** 2021-05-27
- **Target enrollment:** 192 (ACTUAL)
- **Last updated:** 2021-08-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02923700

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02923700, "Leukocyte-rich PRP vs Leukocyte-poor PRP for the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02923700. Licensed CC0.

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