Aprepitant- and Olanzapine- Containing Anti-emetic Regimens With High Dose Melphalan

Conditions

• Nausea
• Vomiting

Interventions

• DRUG: o Aprepitant 125 mg orally one hour prior to chemotherapy on Day -1 and 80 mg orally on Days 0 and +1
• DRUG: Olanzapine10 mg orally daily on Days -1,0,+1 and +2
• DRUG: Aprepitant plus Olanzapine

Sponsor

Rush University Medical Center