# Can We Save the Rectum by Watchful Waiting or TransAnal Surgery Following (chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer?

> **NCT02945566** · PHASE2,PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **University of Birmingham** · enrollment: 380 (estimated)

## Conditions studied

- Adenocarcinoma of the Rectum

## Interventions

- **PROCEDURE:** Standard TME surgery
- **DRUG:** Long course concurrent chemoradiation with capecitabine and radiotherapy
- **RADIATION:** Short course radiotherapy

## Key facts

- **NCT ID:** NCT02945566
- **Lead sponsor:** University of Birmingham
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2017-06-14
- **Primary completion:** 2027-04
- **Final completion:** 2028-08
- **Target enrollment:** 380 (ESTIMATED)
- **Last updated:** 2025-03-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02945566

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02945566, "Can We Save the Rectum by Watchful Waiting or TransAnal Surgery Following (chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer?". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT02945566. Licensed CC0.

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