# Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

> **NCT02946996** · PHASE2 · TERMINATED · sponsor: **Medical University of South Carolina** · enrollment: 41 (actual)

## Conditions studied

- Prostate Cancer

## Interventions

- **DRUG:** Metformin
- **OTHER:** OPC

## Key facts

- **NCT ID:** NCT02946996
- **Lead sponsor:** Medical University of South Carolina
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2016-12-28
- **Primary completion:** 2023-12-05
- **Final completion:** 2024-08-19
- **Target enrollment:** 41 (ACTUAL)
- **Why stopped:** Investigator retired from clinical practice prior to enrollment goal being met.
- **Last updated:** 2026-03-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02946996

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02946996, "Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT02946996. Licensed CC0.

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