# Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Versus no HIPEC in Locally Advanced Colorectal Cancer (APEC Study)

> **NCT02965248** · PHASE3 · UNKNOWN · sponsor: **Fudan University** · enrollment: 147 (estimated)

## Conditions studied

- Locally Advanced Colorectal Cancer

## Interventions

- **DRUG:** Standard adjuvant systemic chemotherapy
- **PROCEDURE:** Hyperthermic intraperitoneal chemotherapy (HIPEC) with raltitrexed
- **PROCEDURE:** Hyperthermic intraperitoneal chemotherapy (HIPEC) with oxaliplatin

## Key facts

- **NCT ID:** NCT02965248
- **Lead sponsor:** Fudan University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2016-11
- **Primary completion:** 2021-11
- **Final completion:** 2023-11
- **Target enrollment:** 147 (ESTIMATED)
- **Last updated:** 2018-06-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02965248

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02965248, "Adjuvant Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Versus no HIPEC in Locally Advanced Colorectal Cancer (APEC Study)". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT02965248. Licensed CC0.

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