# : Vascular Function in Health and Disease

> **NCT02966665** · PHASE1 · RECRUITING · sponsor: **Russell Richardson** · enrollment: 420 (estimated)

## Conditions studied

- Chronic Obstructive Pulmonary Disease
- Pulmonary Artery Hypertension
- Heart Failure
- Hypertension

## Interventions

- **OTHER:** Maximum Exercise Tests
- **DRUG:** BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate
- **DRUG:** BQ-123
- **DRUG:** Fexofenadine, Ranitidine
- **OTHER:** Angiotensin-II, Valsartan
- **DRUG:** Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine
- **DRUG:** BQ-123, MitoQ, BH4

## Key facts

- **NCT ID:** NCT02966665
- **Lead sponsor:** Russell Richardson
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2008-09
- **Primary completion:** 2026-08
- **Final completion:** 2026-08
- **Target enrollment:** 420 (ESTIMATED)
- **Last updated:** 2025-09-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02966665

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02966665, ": Vascular Function in Health and Disease". Retrieved via AI Analytics 2026-09-16 from https://api.ai-analytics.org/clinical/NCT02966665. Licensed CC0.

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