# Effect of High-dose Naloxone Following Third Molar Extraction

> **NCT02976337** · PHASE2 · COMPLETED · sponsor: **mads u werner** · enrollment: 23 (actual)

## Conditions studied

- Healthy Subjects
- Hyperalgesia
- Inflammations, Endodontic
- Pain, Acute
- Sensitization, Central

## Interventions

- **DRUG:** Naloxone
- **DRUG:** Normal Saline

## Key facts

- **NCT ID:** NCT02976337
- **Lead sponsor:** mads u werner
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-10-12
- **Primary completion:** 2023-11-27
- **Final completion:** 2023-12-27
- **Target enrollment:** 23 (ACTUAL)
- **Last updated:** 2024-02-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02976337

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02976337, "Effect of High-dose Naloxone Following Third Molar Extraction". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT02976337. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*