# JYNNEOS Smallpox Vaccine in Adult Healthcare Personnel at Risk for Mpox in the Democratic Republic of the Congo

> **NCT02977715** · PHASE3 · COMPLETED · sponsor: **Centers for Disease Control and Prevention** · enrollment: 1600 (actual)

## Conditions studied

- Monkeypox Virus Infection

## Interventions

- **BIOLOGICAL:** JYNNEOS (Liquid Formulation)
- **BIOLOGICAL:** JYNNEOS (Lyophilized Formulation)

## Key facts

- **NCT ID:** NCT02977715
- **Lead sponsor:** Centers for Disease Control and Prevention
- **Sponsor class:** FED
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2017-02-23
- **Primary completion:** 2025-10-31
- **Final completion:** 2025-10-31
- **Target enrollment:** 1600 (ACTUAL)
- **Last updated:** 2026-04-23

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02977715

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02977715, "JYNNEOS Smallpox Vaccine in Adult Healthcare Personnel at Risk for Mpox in the Democratic Republic of the Congo". Retrieved via AI Analytics 2026-07-07 from https://api.ai-analytics.org/clinical/NCT02977715. Licensed CC0.

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