# Cryptococcal Antigen Screening Plus Sertraline

> **NCT03002012** · PHASE3 · TERMINATED · sponsor: **University of Minnesota** · enrollment: 22 (actual)

## Conditions studied

- Cryptococcosis
- Cryptococcal Infections
- AIDS-Related Opportunistic Infections

## Interventions

- **DRUG:** Sertraline
- **DRUG:** Placebo Oral Tablet
- **DRUG:** Fluconazole

## Key facts

- **NCT ID:** NCT03002012
- **Lead sponsor:** University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2017-11-15
- **Primary completion:** 2018-03-13
- **Final completion:** 2018-03-13
- **Target enrollment:** 22 (ACTUAL)
- **Why stopped:** SAEs with n=1 serotonin syndrome, n=2 SAEs after sertraline interruption.
- **Last updated:** 2020-06-09

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03002012

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03002012, "Cryptococcal Antigen Screening Plus Sertraline". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT03002012. Licensed CC0.

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