# The Effect of Acute Tryptophan Depletion (ATD) on Esophageal Sensitivity in Healthy Volunteers

> **NCT03017768** · NA · COMPLETED · sponsor: **Universitaire Ziekenhuizen KU Leuven** · enrollment: 15 (actual)

## Conditions studied

- Esophageal Sensitivity

## Interventions

- **DIETARY_SUPPLEMENT:** Acute tryptophan depletion
- **DIETARY_SUPPLEMENT:** Placebo
- **DEVICE:** Multimodal stimulation probe

## Key facts

- **NCT ID:** NCT03017768
- **Lead sponsor:** Universitaire Ziekenhuizen KU Leuven
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-06
- **Primary completion:** 2017-03-24
- **Final completion:** 2017-03-24
- **Target enrollment:** 15 (ACTUAL)
- **Last updated:** 2017-06-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03017768

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03017768, "The Effect of Acute Tryptophan Depletion (ATD) on Esophageal Sensitivity in Healthy Volunteers". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT03017768. Licensed CC0.

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